The Orientale impact basin is the youngest and most well-preserved of the lunar multi-ring basins. The generally well-preserved ring structures and basin facies are distinctly anomalous in the southwestern quadrant; the outer Cordillera ring extends significantly outward, the Outer and Inner Rook mountain rings are more poorly developed and show anomalous characteristics, and the Montes Rook Formation varies widely from its characteristics elsewhere in the basin interior. Based on the gravity, image, and topography data, we confirmed that the southwest region of the Orientale basin represents the location of a pre-existing similar to 320 km rim-crest diameter peak-ring basin centered at 108.8 degrees W, 28.4 degrees S, and characterized by an similar to 170 km peak-ring diameter. We model the structure and morphology of this large pre-Orientale peak-ring basin (about one-third the diameter of Orientale) and show that its presence and negative relief had a distinctive influence on the development of the basin rings (disrupting the otherwise generally circular continuity and causing radial excursions in their locations) and the emplacement of ejecta (causing filling of the low region represented by the peak-ring basin, creating anomalous surface textures, and resulting in late stage ejecta movement in response to the pre-existing peak-ring basin topography. The location and preservation of the peak-ring basin Bouguer anomaly strongly suggest that the rim crest of the Orientale basin excavation cavity lies at or within the Outer Rook Mountain ring.