The end-Permian Emeishan Large Igneous Province (ELIP) in SW China is widely accepted to have formed by mantle plume activities, forming voluminous flood basalts and rare picrites. Although many studies were performed on the petrogenesis and tectonic setting, the detailed conditions and processes within the magma chamber(s) remain unsolved. In this study, we studied the sector-/oscillatory-zoned clinopyroxene (Cpx) phenocrysts and performed Cpx-liquid thermobarometric calculation to constrain the physicochemical processes within the magma chambers. The results show that Cpx phenocrysts from the high-Mg basalts were crystallized at 4-27 (average 17) km, whilst those from the low-Mg basalt were crystallized at 0-23 (average 9) km depth. The sector and oscillatory Cpx zoning in the high-Mg basalts show that the magma had experienced undercooling and multistage recharge events in the deep-staging chamber(s). The magma replenishments may have eventually led to the eruption of high-Mg basalts, and magma ascent to the upper crust for further fractionation to form the low-Mg basalts and mafic intrusions.