Spatialization of soil formation rate (SFR) is always a difficult problem in soil genesis. In this study, the dissolution rate in karst areas of China during the period 1983-2015 was estimated on the basis of geospatial analysis techniques and detection of variation via the law of chemical thermodynamics in conjunction with long-term serial ecohydrology data. SFR at different lithological backgrounds was calculated on the basis of the content of acid-insoluble substances. Results showed that the spatial dissolution rate of carbonate rock ranges between 0 and 106 mm/ka, averaged at 22.51 mm/ka, and the SFR ranges between 10 and 134.93 t km(-2) yr(-1), averaged at 18.59 t km(-2) yr(-1). The dissolution rate and SFR exhibit a slight increasing trend with 0.04 mm/ka and 0.003 t km(-2) yr(-1), respectively. The risk for soil erosion was reevaluated on the basis of the SFR results, and the area with erosion risk and the ecologically safe area were corrected. Results indicated that the area with erosion risk is four times higher than the ecologically safe area. This study will hopefully instigate and facilitate the application and popularization of geospatial analysis technology to the research field of rock weathering and soil formation.